Kivara Neurosciences

The Future of Neurodegenerative Disease Begins with Earlier Detection

Kivara Neurosciences is developing next-generation diagnostic technologies designed to identify neurodegenerative disease risk before irreversible damage occurs — enabling earlier intervention, better patient outcomes, and more effective therapeutic development.

Disease begins — invisibly
Misfolded proteins accumulate. No symptoms. Conventional tools detect nothing.
Time to diagnosis
-17.5 yrs
Brain function
97%
KIVARA WINDOW-25y-20y-15y-10y-5yDx

By the Time Symptoms Appear, the Damage Is Already Done

Neurodegenerative diseases progress silently for years — sometimes decades — before clinical symptoms emerge. By the time patients seek care, substantial neurological damage has often already occurred, narrowing the window for meaningful intervention.

0M+
People worldwide living with dementia today
0M
Projected global dementia cases by 2050
0%
Of dementia cases attributed to Alzheimer's
0 yrs
Of silent pathology before symptoms
Phase 1
95%
Healthy
Normal cognitive function
Phase 2
70%
Silent Disease
Pathology accumulates
Phase 3
40%
Mild Cognitive Impairment
Subtle decline begins
Phase 4
15%
Alzheimer's Disease
Clinical symptoms
→ Kivara targets the silent phase — where diagnostic intervention is most valuable.

Healthcare Is Transitioning from Reactive Care to Predictive Medicine

The most valuable companies in medicine over the next two decades will be those that enable identification, stratification, and monitoring of disease — not those that simply react to it.

Past

Reactive Care

  • Diagnose disease after symptoms appear
  • Treat symptoms, not biology
  • One-size-fits-all therapeutics
  • Limited longitudinal monitoring
Future

Predictive Medicine

  • Identify disease risk before symptoms occur
  • Monitor biological progression in real time
  • Guide targeted therapeutic intervention
  • Track treatment effectiveness longitudinally

Diagnostics are the critical infrastructure of this transformation — the layer that makes everything else possible.

Investors reviewing healthcare and biotech market performance on trading floor displays

A Multi-Billion Dollar Opportunity

Three converging markets — biomarkers, Alzheimer's diagnostics, and broader neurodegenerative diagnostics — are growing rapidly as the global burden of disease accelerates and disease-modifying therapies require better patient identification.

20242030

Neurological Biomarkers Market

2024
$0.0B
2030
$0.0B
CAGR
12.9%
Growth
+106%
Industry analyst reports, 2024
20252033

Alzheimer's Diagnostics Market

2025
$0.0B
2033
$0.0B
CAGR
11.2%
Growth
+134%
Market research consortium, 2024
20262031

Neurodegenerative Diagnostics

2026
$0.0B
2031
$0.0B
CAGR
7.6%
Growth
+44%
Precision medicine outlook, 2024

Diagnostics Capture Value Across the Entire Patient Journey

01
Patient Screening
02
Risk Identification
03
Early Intervention
04
Therapeutic Selection
05
Treatment Monitoring
06
Longitudinal Disease Management
A single platform serves
PatientsPhysiciansHealth SystemsEmployersHealth PlansPharmaceutical CompaniesClinical Trial Sponsors
Biotech executives reviewing therapeutic pipeline in a modern boardroom

Breakthrough Therapies Require Better Diagnostics

Billions of dollars are now flowing into neurodegenerative therapeutics. But these therapies only work when the right patients are identified at the right time — creating direct, structural demand for diagnostic platforms like Kivara.

Earlier patient identification
Better patient stratification
Biomarker-driven enrollment
Longitudinal monitoring
Plasma sample vial next to a patient stratification report
Diagnostics + Therapeutics

The Companion Diagnostic Era

Therapeutic Investment
Pipeline activity in neurodegenerative disease
$50B+
FDA-Approved DMTs
Disease-modifying therapies require selection criteria
Growing
Trial Failure Rate
Often due to late-stage patient enrollment
>90%

More Than a Single Test

Kivara is being built as a platform — one core technology, many indications. Each future application compounds the value of the underlying science.

Kivara
Platform
Alzheimer's Disease
Mild Cognitive Impairment
Parkinson's Disease
Lewy Body Dementia
Frontotemporal Dementia
Neuroinflammation
Therapeutic Response

Converging Trends Are Creating a Historic Opportunity

Aging Global Population

1B+ people over 60 by 2030

Healthcare Spending Growth

$10T+ global market

Precision Medicine Adoption

Standard of care shift

Biomarker Validation

Plasma & digital biomarkers maturing

AI-Enabled Diagnostics

Pattern recognition at scale

Disease-Modifying Therapies

Approved & rapidly expanding

Demand for Early Intervention

Patients, payors, and providers aligned

Why Kivara

01

Massive Market Opportunity

Multi-billion dollar diagnostic and biomarker markets growing at double-digit CAGR.

02

Prevention-Focused Healthcare Shift

Aligned with the global pivot from reactive treatment to predictive medicine.

03

Scalable Diagnostic Platform

One core technology engineered to support many future applications and indications.

04

Multiple Future Indications

Alzheimer's, Parkinson's, FTD, Lewy Body, and beyond — each a multi-billion dollar market.

05

Companion Diagnostic Potential

Positioned to power the next wave of disease-modifying therapeutics.

06

Strategic Acquisition Potential

Diagnostic platforms are among the most strategically valued assets in precision medicine.

Building the Future Standard for Neurodegenerative Disease Detection

Kivara Neurosciences is pursuing a future where neurodegenerative diseases are identified years before symptoms emerge — enabling earlier intervention, accelerating therapeutic innovation, and transforming the standard of care for millions of patients worldwide.